J 1 5 V \ ^o^ T£Uc<i(lAPrt M£. 33 -Jo C- OCfllV^v "S>U<A. SF L •IE nrifl PITTSBURG, CALI FORUM* INSTRUCTIONS 1. To secure adequate patent rights is an im- portant purpose of this book. Only properly kept records will assure The Dow Chemical Company of such protection. When starting a project or experiment, write in precise lan- guage your purpose and general plan of pro- cedure. Record your work as you progress, giving sufficient details. Handwrite directly in the book. Do not make notes on loose paper to be copied later. 2. All entries should be in permanent, black ink. Do not use pencil. 3. The subject or title of the experiment and the book number should be accurately re- corded at the top of each page. The date should be recorded at the beginning of each day's work. Note all absences such as trips, vacation, illness, etc. 4. The various acts or experiments completing one or more projects may be recorded exactly chronologically, thus possibly mixing refer- ences to one subject with those to another, or space may be reserved for the complete re- cording of one experiment in one place over several days, as you prefer. If the latter course is adopted, indicate at the start of the next experiment how many pages were re- served for the one before it. Give a complete accurate account of what you did and what resulted. Enterallresultsgood or bad. Incase of error draw a line through the incorrect words. Then continue with the correct word- ing. Copious descriptions with elaborate de- tails are preferable. Do not use private ab- breviations or Company nicknames without frequently denning what they mean. Always keep in mind the necessity of original data to prove any new discoveries. If any portion of a page of more than two lines is left blank when that page is finally completed, draw a diagonal line through the space and write your initials and the date on the line. If it is necessary to insert graphs, etc., in the book, attach the insert along one edge only and use the page under it in the usual manner. Names of witnesses who are present during the work should be recorded. Also the names of people with whom the work was discussed or to whom samples were given for analysis or testing. The dates of these acts should be recorded. It is also most desirable to keep a file of other papers relating to your work, e.g., analysis sheets, test request sheets, purchase orders, test results, etc., One or more scientifically trained witnesses should read and understand the pages covering each week's work and sign and date your book at least once a week. The witness form pro- vided in the book every twenty pages also should be filled in. The witnesses must not be those who are co-discoverers with you of any of the work recorded. New concepts, new solutions to problems and new ideas, plans or procedures and sketches should be recorded immediately in this book at the time they occur. When they are be- lieved to be patentably important or when experiments show results of possible pat- entable importance, they should be disclosed to and understood by your co-workers. The best possible proof of your discovery is to have someone who is scientifically trained repeat the work and record it in his own book. Whenever possible, have one of your co-workers repeat your work and note this fact in your book. In particular, when an experiment shows results of possible patent- able importance and especially when no wit- nesses were present, have someone else re- peat the experiment as promptly as possible. This notebook and all information recorded therein are the exclusive property of the Company. All contents are strictly confi- dential. You must take every precaution to safeguard this book against loss or damage by fire, water, etc. SCIENTIFIC BINDERY PRODUCTIONS CHICAGO S. ILL. iW>v 2ov«v»»v\ fs^vnes u>t4Vt»v%. CarowV»» V C^c-Wcs ' CA-tP, MMt>A (an> t5fe*u»r«-. cA^o »> - ^-i )— CV C4v ° v r\ ftem M6t>A» MM** ^ NMOA-2. TMA ^n.) erf ay' MTT>A <> , / On t^MOA-^ MMOA- 4 |*MOA-£ TWA- 4 TMA T*A-(. M .. TABLE OF CONTENTS PAGE No. tfeSCAMf^lc So&TecTive" (i€SPb*j&e ^i-n BfcSlS Pofc. W-O. CALcOLAfftOiO ^ 1 ' TMft so^-pojtc evfVuoM\oto S ofeJecTvvje £^s Pot^se"3 <t so^xecTt^e &&%Vc*±2>e: ZTt^tt i\GH So^-Acotg: evAu.of\-no<0 2.0 MHWk Sob* fcco-re &viu.o&'n©K5 . 2il^°* SOBSrfi'c.Tvve R.eSPd>oSeTS *l. ^SfcCTw/e ^ESPoKi&^'S- 2S,Z4,2£ ^o^^ )lo i U3.U4J. U(J 1^02.^3 fte&A SobAcOTv* £0ArvUAT*C>fs3 3<T MTD& Sofc^cOTb £0*vxMT\ot^ K Mbfc ^0fe|i«coT6 E^&L'MTlOiO > 31 . 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(j • \ 1 -IE DOW CHEMICAL COM PAN UNIVERSITY OF CALIFORNIA MEDICAL CENTER SAN FRANCISCO 22, CALIFORNIA 5EARCH AND DEVELOPMENT LABORATORY 29 AugUSt 1962 Doctor Sasha Shulgin Dow Chemical Company Walnut Creek, Calif. Dear Sasha: JAY & myself tried the MMDA on Sunday, 26 of August. Our log follows: (taken by (cAR£M up to 11:30) 10:21* 100 mg orally 10:55 felt reaction, saw slight green tinge in shadows of faces. Pupillary dilitation CC. No dilitation for W. L., but he felt "layback." 11:05 Volluble, constant movement of hands & feet (as per usual for me) ¥. L. experienced the "floats." 11:10 CC felt warmth & muscle "tone" (almost quivering) 11:30 Departed for Marin country with U£>V (originator of tjjr Y v^S-) 1 Shopped in supermarket at about 0.8g. 12:30 Arrived at home of WAIZTY <W Nj\ncy (Magnificent oriental stage in living room.) 1:00 Picnic with no effect on taste. Still .8G, very pleasant 2:00 Experience comparable to 20 MG LSD 25. 2:30 Feeling relaxed, composed 3:00 Back to normal; feeling of having taken amphetamine. 3:30 Returned homej approx. .9g. U:30 Slight feeling of "green apples" in stomach 9:00 Eyes still dialated; a little restless but slightly tired 11:00 To sleep. Slept well. Awoke refreshed and happy. /W//Y q J THE DOW C-H-E-M-I-GA-fe— COM PAN ^y BOOK NO. Observations on. FsychoouuW £f foots of Methoxy "ethylene ,ioxy Amphetamine ?vi^6 \ 11:20 a.m., Saturday, September 1, 1962 - 210 mg. MMDA orally TC MMDA tastes awful. The bitter alkaloid taste is followed by a 5? distinctly chemical laboratory flavor as it' from old rubber tubin J This is easily dissipated by a drink cf fruit juice and cookies. J» othing ^eems Co happen for about kS minutes when rather suddenly an anvil seems to lower itself over -"our head; you feel disoriented, / and tend to withdraw from socia t a little. In an hour you ^ feel like wandering ofi into the hills e alone. This drug gives U» less feeling of being ill than mescaline. feet definitely •^ reaches a climax with a pleasant afterglow following. rarently there is no profound motor coordinati or ■• . Although I didn't ^2 feel too steady, I could run down hill at full speed without falling. ^ Would probably have trouble jugglinc thou j?P 200 mg. yMDA yields that "Sunday afternoon" feeling of desiring to lie down and enjoy life; a luxurious feeling of "layback." No enhancement of colors in visual scene (except some greenish tinge in faces) but on closing eyes hallucinations appear to be quite real in 3-D; like watching a movie. hirst these dreams appear in black and white but later color starts a; In.-. Chartreuse and magenta first aopear, then blue and finally red. First had visions tinued on pa»re 2) 1 1 j i_j T~irE"T>l AL COMPffNT BOOK 25 larere numbers on garni brin ? oetween the a US „ Le down ana su , 3 t be he per s] heat - just a comfortable wt peac on. ful, 3D and a or a more e , enjoyin .elds rees more than beinp- in Commentary on e: f had a affed iave SWO rn it ■"" »nta fuscia and chart 7her the re st Then marv ie trans sphere chartreuse, blue, .. icn cascaded down a gla 9g< There is the wor] I don't remember the time ago. visions. The Dig tendency is s . ck, not necessarll etely J 1 L A THE DOW CHEMICAL COMPANY enjoy this feelJ oua lor.-or. 'i an: pre I feel just i incoherent, itly atoxic Here, 1 Ju ° ee ' ^pletely relaxed by and just with the world and ' h111 ' ' among the fields , U ' But t:;6n * littl6 later Iwa lie down wit and visions. ' The euphonic state comes ,ts start we, *els w the aals as tne "a I think •He-nt ™ ** 3ub - i » a 1 i 1 1 1 e mscious without goin feeling o i aall.atio feet were detached fr side; an illusion somewhat akin causing the light-, of a cigarette%ppear to detach ! f the c -tte when waved in a semi -Oar. Just now Loain- my eyes, ""! -'liant regal purple velvet encrusted w ie wnite back-round. The scene changes to a rid n effulgent light pervading every t !lo "' J toWe S However, he eyes, the cene becomes drenched in brilliant .b warmth usness pervaded me as the DOW CHEMICAL COM P, recently expert "pA^ 1 r ' iis me"< es te is riru Ld sell slaxan Lant. The ulysts shr it i fact it proves to be as Tie a conscious acious. It ^eems dreams a rfhile awak real appear!' scenes fill in the movies. 1 nave never felt rofoundly It fin -.' . ted J ' THE DOW CHEMICAL COMPANY // -// Si-] -fl J~wv^- a pfiJ •*' U /- \Ji K_ MMDA / MINIATURE HIGH J UWe ^ **<*/• T use the word miniature in the spnse that I would describe a niece by the jazz nianlst Bud Powell 33 • miniature. Coir- j rinsr a c eethoven niano sonat* with Autumn in i*ew York ■■ « " as ol-yed by Powell would, be an^lagous to com~«r^ng attMl and /to M ■tLoa oilijno . MN!DA domes through as a miniature hirh -- everything is there but in lesser quantity and duration. VVDA s tors barely short of the Olvmnian Universe of tiire- ceasing and organic and inorganic rad'apces ». i'he immediate ^art of the hlflji Is about two and ^ne hnlf hour? in duration, Hather than a cessation of Time, as there is with m^sclin or rsilocvbln, there is a kind of time! a ssn-ss during the first m l^iselike hour of the high. There is morn <?£>a feeling of stur>pf act ion than th»re is with most highs. In a car climbing theJBerk°ley foothills I went into a ter- rible fear, *-/•'•', €ne i^iphti Vor-at •^l&f&.S'pdA.'s It only lasted a few minutes -- but it did not matter in the tlmeles«ne ss how long the nanic lasted A it was eternal. I looked out onto the grassy hillside at the dead silver-brown grass, in the exnanse of field I could se- each separate blade of grass gleaming K±±bi and the THE DOW CHEMICAL COMPANY trillions of brown-silver blades blended together into a vast wavering fur. *'' ar below was the nanorama of foggy Berkeley and Oakland and the bay. --It all began to loom 5n tlmeles^nesa and beauty. --1 thought I was going to °nt. a r the Olympian Universe. I WAS NOT P EPARiD FOR rr ' T : - OLYMPIAN \WA I --I had been expecting something like mari.1uana A 1 realized that if I sneered the Olympian that I hadn't yet recovered aufflc- ientlyjfrom my last high to hold myself together. Heat swelled in my genitals and rose to my stomach. --I felt ^Uv agonizing ££$■ ^FgfyfB&f 3 ar . I wanted to a* the others to go back so 1 could rake thorazine. i couldn't talk. The car swerved around a hair in oend in the road giving me another view o^ the silverbrown g^ass-fur and the vast unwar ted dearness of the ?>w. Suddenly I was fighting with 'Obtain Zero 1 -- I mean the whole disor^ ~ed and et or, ni ty-se^king consciousness that is no longer mammalian in mature but belongs to the order of molecules and in^rt matter 1 . I decided th - 1 a 1 1 i could do wasto go with it -- to let ^ero take over, put then 1 was su'-e that T would not come back. *iian I tried to hold back the high but 4^ realized I would do mvself dcjnage that way. Then I tried to get on top of the whole high and control it. -ill in all. I tried perhaps iJ., y L -v- almost fifteen or twenty mx*m±±*1mxxm± unrecnllable -aori undescrioabl* means to /Jdih4^ control or escane the high. Ehirnlgfe this time I believed that I was goine to nieces and I would possibly never be with the human-world again. V? insides were eoing wild and my conscious mind s^em~d to be the only force ho ding me together. At one ooint I managed to ask 29 30 how the 'oaaj J b oo n figured. --I was "°as°n"^d by com aring - dosage to masculine dosage - ; ro? a moment I grasned the fact that I could go through three hours of the f -ar . ±hen my insides and mind vent wilder. o esus y I could not ^nt^r Olvmnia again'. '. When the car sto "ed I was in co.^rol and the aroused mol- ecular consciousness had dis~i aced. ihe number of exits and ■ratiKRJt ordinary animal no.ers that I {*£& tried had giv^n me con- trol, l account the sudden g ng of ?ur^n-s? to »4de ex- neri nc^ with p(jy lucinog^r.s . 1 don't think my of the methods that I tried worked -- b\it the number of ooss ioilitles pave me an as'urflno" i^st I could control me even in Olyirria. 1 told the others what had ha rened fc ftinv and felt I could -n.loy somo rf ; h* day. ' '» « ' ' ' ' ' ' ' f I / In - ^r^stinsly , none of th ,j oth^r oart ici-ants got tc the Olvmrian Universe iurine the hitfh. I accent th^ fact that I ^-£t i>gcnO M t5 ' ' ' ' ' ' ■ £* touched ^pf^os^am && - {LvJ . v i»ii.-^>- wpeyote and osllocybin. As wp w". k r -d ijc the fr tcath ov°r ffolden brown dust I saw ftfttls footprints of birds, tennis* sho Q s, and bare feet. The frightening nature of tracks and artifacts beirar to quchxxjiIixji ov°rwh^lm me. \3 T walked T tri d to insulate myself from the sipbt. To my right wasthe d^eam ranor .ma of hundreds of smare mil-s of enchanted cities and dr- mreality fog "ouring uoon th-m from the hay. 1 wisnot interested and oniv cared about k^oinp- myself together and not slicing back to m et Captain Z^ro . The dnort, et-rnal. urhill walk exhausted us nnd we fell on the ground in a tiny stand of tr es . I still wanted the ex- ■THt-DOW- C i end and return to the me nines and realMies.^6% I had adjusted enough to make it through the high. My companions closed -ye 3 and t having brain my eyes movies, (^arlier sqoquu had b ^n forced shut many times oy hied mv ?yes o"»m 3 o, \np stark reality exactly <s I sa> it t. S ^.4 the -u'horlc hallucinogen :'■ asure.) Now not wanting in movies or visions. '.Yhen I clos d ny s ex- perimentally I saw on] y .s and -inp blackness. We talked desu^.tor and dozefully and I real iz~-d that I was aMe to s- a through the 'yes o r my corrnanions . Th p y were . I talk r^&bO Vrft ^\s-\1\Lf*^0f I found t Iking too ' t . V.y toe: ion and r ~e. Vh=n I icaret 4 «s 1 c Lnd ray lira well and they were numbed. Matches kent ut in a wind that was not strong enough to blow them out. '/<e wobbled when we walked. We stayed in tl ° sand of tr oo s . I sat for a wrile then got u* and sat ir nother Dlac°. "Then I got u^ again & etc. 8 Exc nt for visual sensation, which w*s lust ^n the verge of mescaline or "silocy In vision in c ' a ri ry , I d to be se°l d from sensation and living In a kind of hyner-lucidity of sense -- a 3 ant paradox. I 1 ay iack and closed my eyes and Jtis d raising the goddess Kundal ini ( x he Se"^nt Power) from the base chakr a t ■ through mv nody. I XMMJUUtix±xxmm.m.m.dni succ- ed"d in raising the Dower, for the first time, past my shoulders and into my head. I r^aliz^d, as I did it, that I was not truly raising the! Seroent Power but rather cleaning the nerve tubes. However, I achieved 32 THE DOW CHEMICAL COMPANY BOOK NO. SUBJECT DATE -1 1 — i 1 1 1 — i 1 1 — i r gr^ylsh-clear affective nictures ' "3. It was a g^od feeling. The crystal clear air gave bright gr^en sharnness to th" ev=rgr«°ne. Look Tig at tr-es of leaves or olants whs like a mild mescaline high. Fir tr es b»cam-- living, gr°»n, modern 3ci)lDtur°s o f ' strange Indian rococo blasts -- is If th sculotor Linschitz worked at th e ir trimming. Th" malals'llke feeling b°pn to "nd tic 5 the dozeful feeling / w i th it. I walked to a r°dw-nd corse wh°re oth"r members of th* 1 narty were sitting. I was struck by th" absolute and superb fcraix beauty and clarity o :' the peonle and the trees and air and the music that played over the por' .ble ^adlo. I felt close to the children and admired their beauty, fct this noint I realized that 1 was sim-ly sitting and n joying a Sunday noon tXx in its*~t\)ll nle-.s ntness. Ordinarily I would nave been bored with out more to do. r he next couc 1 - of ho rs became a pleasant and ^ beautiful nicnic. x he come-down was abru-t but «*t unr 1 "asant . ■***<*, ^ime mssed with swift rapidity for the rest of theday. Two hour -eriods would flash by. Lat.p -hat night I was kept from glPPt) ^nr half an hour by brain movies — 11 ' tie crocodiles running across dusty roads through spotlights in the da-kness, * magic eve~gre"n tr"es fading into and out of u*±±? reality, and «juut±ata*xx anecdotal sequel ^ J. THE DOW CHEMICA AH rE A w<v-k after raking VWDk I woke in the middle of the night and as I awakened I felt that there wo^ld be no reality but only nothingness. I was horrified and threw myself bolt upright in bed and opened my c yes instantaneo\isiy . 8helley says: Lift not the painted veil which those who live call Life* though unreal shapes be pictured there. "T y|nd *i&v but mimic all we would Del ieve with colors idly soreadybehind lurk Pear ^nd Hops .t3rin 0estinies» who ever weave "Their shadows oer the chasm sightless and drear. . • The awakening I had was definitely a reaction to the WMDA. Yesterday I talked with a man who has tak^n too much lsd. I tried to avoid son king 01 hallucino ens but h^ wts insistent. As I described sotp post-In llucinogen states of extr me anxiety regarding the nature of reality, the man began to writhe in his chair, wring his handstand io»^ the abllitv to speak»£e*idD»lr^ J&frt I have be<n in that state. While sneaking with. R-^_ he identified it as an anxiety state and pointed o\it that it is not only related to hallucinogens ut is a not uncorrron anxiety state for those who haveinot had drugs. •■o 0,, accounts the state to an arising of «6»conscious material to the surface. at s<=- ms f 'lTiA and *hat 1s ' ring as hit er, What it d -)<- 3 ri C'a the intuitions that T hav° that strengthen and contradict °*ch ot-er. I am awa^' of two f^ lings: ftV.at the 'material ' is of a r°nr«s°ed psychological nature in th e Fr^u^ ian-Reichian sense, and that ther c is also another order of'mate-ial' confront ~d. The other or^^r is that of the molecular lev~l of consciousness. I mean a nart of ourselves more related to th» philosophical k*ju«±*m« consciousness of s«a urchins arid sronees -- who are no mere than the tugs of th°ir desires arid hungers and rhe consci nsn-sses of their motions and withdrawals -- who ar= an actual conscious oart cf the -dnvsical universe and th° actual b^injr of their oro^oolasm in the 'Surge of Life. 1 It would e inter es'ing if what we so surelv call the - ftubcnsc d . '- M o o-p . Uncoaacious were in reality two or mor e vastly divided ~art«v r b^inp that a^e both comironly unacn^.-si le. I am not sayir.ff this to strnah'n mv argument uhat I con- fronted th" molecular consciousness on N'VD.i. I was in too much of a fear state to be definite of anvthing »hen I think of it now t w w^eks later. -- But I am intuitively sxxJtfcliB sure that we are m-eting two unknown areas -- both repressions and a n«ijicMJttr m ^lecular-DhilosoT hical-UniverseconcioMsness , I v ave a st^ons fe = llng that vh a second of t v iese should b<=" left untouched by both psychiatry and happy-day inves t lea t l^ns . <Ve mess with som« strucure that should remain unknown -- Unless the experiment- er is a*are of *h P risk -- or ?o^' 9& slo'viv in an investigatory manner with r|^ caution. THE DOW CHEMICAL COMPANY // v\ tin. \jzz_f ifeH, <& v °ici JJU , .x^-Jl*-, A,/» A. *8 /> , "' r * — ** "^ •* » t *■> -% "1 -^r^-*- 9 ' *■ -t- JS-- '\/-v*V, ! i / 36 SUBJECT THE DOW CHEMICAL COMPANY BOOK NO. ^M^loJZl :^ju& ^ MTDA-fW DATE V\\\\i>%- / ^ , M^cM N^-i. * Wrje o lt!\o Pr,v\ . It*, orb '->oon. ? OuwJL- Wo Uo J d' V*o aA- '..-t <A^ 4.1. vJ is 4oU fc*w. Wo *&te2 • 6 '' - 1 * 1 • "1 , T . 1 1 1 1 1 1 1 1 1111 1 . —. THE DOW CHEMICAL CO 37 SUBJECT S*J =a &.<>u^^; cri^ jJ$jiJ£ M\>A 17/ G \ Cfn \u o / 4c '-4©/^ 4.? -? cT\a£ . w4 ^ Wv icrw^. v^*-^ jw^ -xm^-v-u^ w^u, 4 ^ • * 1/ii/t* «//«/*; 4- *>/■ to fcs M J ift. At* fl»U 3<o n ^O (VV\ ■J »4 -Vs\}~ 3. £5 *lNgV c^APji^P-e. itfo,^^. £D.£.rwM«i. ^ciL^v) l o^>4 <^vO^ > .' <i',V)llW\ (1-^ Wirtn^(4« 4—1, (', .Sr-t.^XZ ^ ^t-f^.^, J OQ THE DOW CHEMICAL COMPANY BOOK NO. SUBJECT 5 | v 1 Ux 3/; M/fcJ- (?*- q>iu{ it i \s DATE C*Wo !> Tas )H/\. Ill -»?4 A - <R> \")o Wos 71 v?, - \.0 <W \ J lfl.4, I - 21 .1 UajJL ^1-7- wo". ^ '/J-1 V, 6 ij "^^v-o*. ■ wft o~ - n^ vvaV 4\n? ^^^JL jj. V/cW^ - /o - l 2- ArA/v ~ XJLA THE DOW C HEM hC A L -CO ■<//'?/* "L ^ t o v o . /' I + CL*^vsA_> Vt-O u . 4:w p/u. 0-1 4.(. \v^ f \>t/>^ Ul /1 A\ "'^-V^v. \ - V\* >*iiM-~X . «J. -Hr" \ Is w V)Mll tfV C& ^° ^ 3 AbvU Kjcn *v *J ax. ^S. n '^w a^iu-t _ wj 2..' SO ".*>« •• (m I J T«E DQW-G^ EMICAL COMPA NY BOOK NO. 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