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LSD
Timeline
by Erowid
Jun 13-18, 1966 University of California LSD Conference held in San Francisco, CA.    Details
Nov 16, 1938 Albert Hofmann, a chemist working for Sandoz Pharmaceutical in Basel, Switzerland, is the first to synthesize LSD-25. He discovered LSD, a semi-synthetic derivative of ergot alkaloids, while looking for a blood stimulant. 1  
1943 Professor Ernst Rothlin was the second person to try LSD. Rothlin was Sandoz's chief pharmacologist at the time. Albert Hofmann gave Rothlin a small, 60 microgram, dose of LSD about 1/4 of the dose Hofmann had tried. 2   Details [More Info]
Apr 16, 1943 Albert Hofmann accidentally experiences a small amount of LSD for the first time. This is the first human experience with pure LSD-25. He reports seeing "an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopelike play of colors." The experience lasted just over two hours.   
Apr 19, 1943 Bicycle Day - Albert Hofmann intentionally takes 250 ug LSD for the first time. This is the first intentional use of LSD. 3  
1947 First article on LSD's mental effects published by Werner Stoll in the Swiss Archives of Neurology.   
1949 Dr. Max Rinkel brings LSD to the United States from Sandoz Pharmaceuticals in Switzerland and initiates work with LSD in Boston; Nick Bercel commences LSD study in Los Angeles. 4  
1950 - 1960 Hundreds of papers published discussing LSD.   
May 1950 First article about LSD appears in the American Psychiatric Journal. 4  
1951 CIA becomes aware of and begins experimenting with LSD.   
1951 Al Hubbard first tries LSD. 4  
1952 Charles Savage publishes the first study on the use of LSD to treat depression.   
1953 First LSD clinic opened to the public in England under Ronald Sandison. Separately, unwitting subjects in the United States were given LSD in the CIA funded Project MK-Ultra to test the effects of the drug.   
1953 Dr. Humphrey Osmond begins treating alcoholics with LSD. 4  
1955 First conferences focusing on LSD and mescaline take place in Atlantic City and Princeton, N.J.   
1955 Aldous Huxley first takes LSD. The publication of Huxley's 'Heaven and Hell'. 4  
1959 Josiah Macy Foundation sponsors major scientific congress on LSD. 4  
1959 Allen Ginsberg tries LSD for the first time. 4  
Apr 22-24, 1959 The First International Conference on LSD Therapy produced by the Josiah Macy, Jr. Foundation Princeton, NJ. 5   Details
1960 Harvard University's Timothy Leary establishes the Psychedelic Research Project.   
1962 Congress passes new drug safety regulations and the FDA designates LSD an experimental drug and restricts research. The first LSD related arrests are made by the FDA. 4  
1963 LSD first appears on the streets (liquid on sugar cubes). Articles about LSD first appear in mainstream media (Look, Saturday Evening Post). 6  
May 1963 Richard Alpert is fired and Timothy Leary is dismissed from Harvard. 4  
May 28, 1963 Weil and Russin write a scathing critique of Leary and Albert's work in the Harvard Crimson: Far from exercising the caution that characterizes the published statements of most scientists, Leary and Alpert, in their papers and speeches, have been given to making the kind of pronouncement about their work that one associates with quacks. 7   Details
Feb 1965 Owsley "Bear" Stanley first succeeded in synthesizing crystalline LSD. Earliest distribution was March 1965. 8  
May 8-10, 1965 The Second International Conference on the Use of LSD in Psychotherapy and Alcoholism held at South Oaks Hospital, Amityville, NY 9   Details
1966 Leary founds the League of Spiritual Development, with LSD as the sacrement. 10  
Mar 25, 1966 Life publishes cover article on LSD. "LSD: The Exploding Threat of the Mind Drug that Got Out of Control".   
Apr 1966 Sandoz Pharmaceutical recalled the LSD it had previously distributed and withdrew its sponsorship for work with LSD. 10  
Oct 6, 1966 LSD becomes illegal in California. 11  
Oct 6, 1966 The Love Pageant Rally produced by Michael Bowen and Allen Cohen in Golden Gate Park, San Francisco, CA.    Details
1967 Summer of Love in San Francisco. First human be-in.   
Oct 24, 1968 Possession of LSD is banned federally in the U.S. after the passage of the Staggers-Dodd Bill (Public Law 90-639) which amended the Food, Drug, and Cosmetic Act.   
Summer 1969 Orange sunshine acid first appears. 6  
1970 An estimated 1-2 million Americans have used LSD.   
Jun 1970 Windowpane acid (gelatin squares) first reported by the Bureau of Narcotics and Dangerous Drugs in the U.S. 12   Details
Oct 27, 1970 The Comprehensive Drug Abuse Prevention and Control Act is passed. Part II of this is the Controlled Substance Act (CSA) which defines a scheduling system for drugs. It places most of the known hallucinogens (LSD, psilocybin, psilocin, mescaline, peyote, cannabis, & MDA) in Schedule I. It places coca, cocaine and injectable methamphetamine in Schedule II. Other amphetamines and stimulants, including non-injectable methamphetamine are placed in Schedule III.   
Sep 3, 1971 Albert Hofmann meets Timothy Leary for the first time. 13   Details [More Info]
Early 1970s LSD impregnated paper ("blotter") first hit the streets. Very quickly the paper began being printed with colorful art.   
mid 1970's Blotter paper begins to emerge as the most common form of LSD sold on the street. Previously it had been tablets and powder, but blotter and gel-tabs proved more consistent in purity and potency. 14  
1979 Albert Hofmann publishes "LSD: My Problem Child." 3  
May 2006 Survey results published in Neurology show that both psilocybin-containing mushrooms and LSD may reduce severity and frequency of cluster headaches. 15   Details
Apr 29, 2008 Albert Hofmann dies. 16   Details [More Info]


References
  1.   Hofmann A. "Die Geschichte des LSD-25". Triangel Sandoz Zeitschrift fur Medizinische Wissenschaften. 1955;2(3):117-24. (as cited in Ott J. Pharmacotheon. 1993. pg 123.)
  2.   Horowitz M. "Interview with Albert Hofmann". High Times. 11. 1976.
  3.   Hofmann A. LSD: My Problem Child. J.P. Tarcher, 1979.
  4.   Lee MA, Shlain B. Acid Dreams: The CIA, LSD and the Sixties Rebellion. Grove, 1985.
  5.   Proceedings were published as The Use of LSD in Psychotherapy, edited by H.A. Abramson (1960).
  6.   Lee MA, Shlain B. Acid Dreams: The CIA, LSD and the Sixties Rebellion. Grove, 1985.
  7.   Russin JM, Weil AT. "Corporation Fires Richard Alpert for Giving Undergraduates Drugs: First Dismissal Under Pusey"Harvard Crimson. May 28, 1963
  8.   Eisner B. Interview with an Alchemist: Bear: Owsley, LSD Chemist Extraordinaire. BruceEisner.com
  9.   Proceedings were published as The Use of LSD in Psychotherapy and Alcoholism, edited by H.A. Abramson (1967).
  10.   Ray O, Ksir C. Drugs, Society, and Human Behavior. Mosby, 1996.
  11.   'Getting High: The History of LSD', The History Channel, 1999.
  12.   Bureau of Narcotics and Dangerous Drugs. Microgram. Jun 1970;3(4):2.
  13.   Horowitz, Michael. "Interview: Albert Hofmann", High Times 11:24-31,81 (1976)
  14.   Stafford P. Psychedelics Encyclopedia. Ronin, 1992.
  15.   Sewell RA, Halpern JH, Pope HG Jr. "Response of cluster headache to psilocybin and LSD". Neurology. 2006;66(12):1920-2.
  16.   Erowid. "In Memoriam: Albert Hofmann". Erowid Extracts. Jun 2008; 14:21.