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Ketamine Dosage
by Erowid


Ketamine Hydrochloride is most commonly used as a veterinary anaesthetic. It is generally injected intramuscularly, but can also be taken orally, rectally, or snorted. Much of the ketamine used recreationally is diverted from legitimate pharmaceutical sources in liquid form. Powdered ketamine is usually the result of drying liquid ketamine.

Food should not be consumed within an hour and one-half before ketamine use, and should be avoided for longer periods of time if possible as nausea and vomiting are not uncommon. As always, it should be noted that dosages and reactions vary greatly depending on the individual. Following are charts showing approximate ketamine dosages in mg (by administration type).

  • Nasal / Insufflated
  • Oral
  • Rectal
  • Intra-Muscular


  • Insufflated / Nasal Ketamine Dosages
     by body weightapprox total
    Threshold.1 mg / lb10 - 15 mg
    Light.15 mg / lb15 - 30 mg
    Common.3 mg / lb30 - 75 mg
    Strong.5 - .75 mg / lb60 - 125 mg
    The K Hole1 mg / lb100 - 250 mg

    Onset : 5 - 15 minutes
    Duration : 45 - 60 minutes
    Normal After Effects : 1 - 3 hours



    Powder for nasal use are produced by gentle boiling off of solution. Nasal doses are highly unlinear next to oral and IM doses. The effects are quite different at low doses. A low dose nasally will be short and much different from a comparable oral dose.

    One method described with nasal use is to insufflate (snort) 25 mg in each nostril, wait 5 minutes and repeat until desired dosage is reached.

    Ketamine is often used in 'bumps' or small amounts of the powder insufflated from either a specialized micro-spoon, a specialized 'bullet', or eyeballed small piles. Bumps from bullets are commonly 30-50 mg, although their size varies by size of spoon, make of bullet, and individual. Users should be extremely careful when using a new method of sizing bumps.

    Ketamine dissolved in saline solution (usually at 10% concentration) is also used intranasally. Although it is occasionally prescribed medically in the United States as an adjunct to other pain management strategies, there is no FDA-approved ketamine nasal spray product and it must be produced by a compounding pharmacy for prescription use.



    Oral Ketamine Dosages
     by body weightapprox total
    Threshold.3 mg / lb40 - 50 mg
    Light.6 mg / lb50 - 100 mg
    Common.75 - 2 mg / lb75 - 300 mg
    Strong1.5 - 2.5 mg / lb200 - 450 mg
    The K Hole3 - 4 mg / lb500 + mg

    Onset : 5 - 20 minutes (depending on stomach contents)
    Duration : 90 minutes
    Normal After Effects : 4 - 8 hours

    Oral doses are prepared from a powder by placing the powder in a cup and pouring about 1 cm of hot water (tap should be ok) in it and stiring to solution. The remainder of the cup is filled with an acid such as orange juice. Ketamine itself tastes quite bad.



    Rectal Ketamine Dosages
     by body weightapprox total
    Threshold.3 mg / lb40 - 50 mg
    Light.6 mg / lb50 - 100 mg
    Common.75 - 2 mg / lb75 - 300 mg
    Strong1.5 - 2.5 mg / lb200 - 450 mg
    The K Hole3 - 4 mg / lb500 + mg

    Onset : 5 - 10 minutes
    Peak : 20 - 30 minutes
    Duration : 2 - 3 hours
    Normal After Effects : 4 - 8 hours

    Some who choose the rectal administration route use a syringe with the needle removed. The desired dosage can be put in the syringe, inserted (using lubricant) and injected. Rectal use is similar to oral in that it has a lower peak, but longer duration.



    I.M. Ketamine Dosages
     by body weightapprox total
    Threshold.1 mg / lb10 - 15 mg
    Light.15 mg / lb15 - 30 mg
    Common.2 mg / lb25 - 50 mg
    Strong.5 mg / lb40 - 100 mg
    The K Hole.75 mg / lb60 - 125 mg
    Anaesthetic1 mg / lb100 - 200 mg

    Onset : 1 - 5 minutes (depending on dose and injection location)
    Duration : 30 - 60 minutes
    Normal After Effects : 2 - 4 hours

    It is common to have muscle pain when injecting larger doses of liquid Ketamine into muscle tissue. The pain can continue for several days if it is not administered properly. The muscle soreness can be somewhat controlled by using a very fine (around 22 gauge) needle and by injecting very slowly. It should take 15-30 or more seconds to inject a dose into a muscle. If you feel it begin to sting, slow down the injection rate. IM and IV administration generally produce a higher peak, and a shorter overall duration than other methods.

    I.V. Ketamine Dosages
    Anaesthetic1 - 4.5 mg/kg body

    Onset : 1 - 4 minutes (depending on dose and injection location)
    Duration : 30 - 60 minutes
    Normal After Effects : 2 - 4 hours

    Although some recreational users do inject ketamine I.V., it is uncommon to inject ketamine intravenously. It is commonly used medically for surgical anaesthesia via IV. The book 'Introduction to Pharmacology' by 'Mary Kaye Asperheim and Justin Favaro' 12th edition chapter 12. Page 107.

    Every individual reacts differently to every chemical.
    Know your Body - Know your Mind - Know your Substance - Know your Source.

    Erowid's dosage information is a summary of data gathered from users, research, and other
    resources and should not be construed as recommendations. Individuals can respond
    differently to the same dosage. What is safe for one can be deadly for another.