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Newsgroups: alt.drugs
From: yshan@bcarh697.bnr.ca (Yogi Shan)
Subject: Re: Research information
Message-ID: <1994Jun8.211107.26019@bcarh54a.bnr.ca>
Date: Wed, 8 Jun 1994 21:11:07 GMT

Lamont Granquist wrote:
: synner@cyberspace.com (Ben Lincoln) writes:
: >Hello. I'm doing a research project on various psychedelics and I was 
: >wondering if anyone here has information on any of the following substances:
: >	BZ, STP, and MK-801
: BZ comes up frequently on alt.drugs, but all i ever bother to remember is
: that its nasty...

BZ = 3-quinuclidinyl benzilate

Developed in the '50s; stockpiled as a non-lethal
chemical warfare agent by U.S. DoD until the early '80s.

Related to the JB-series (eg. Ditran) of benzilate
ester hallucinogens.

Synthesis is simple, if I recall correctly:  esterify
3-quinuclidinol with benzilic acid.  I believe it
made a very brief appearance on the streets as either
"TWA" or "DMZ" during the '60s, according to published
sources.  I believe the effects are of the deliriant-
type, similar to datura/belladonna/atropine.

[ correction added 5/97: "Correct statement is that BZ has never been
  available.  TWA & DMZ were benactyzine & Ditran, but I'm not sure which
  is which." -- yshan@nortel.ca ]

Further info, including tox data may be found in 
the "Merck Index", available in the Reference section
of any decent library.


Yogi

=============================================================================

Newsgroups: alt.drugs
Message-ID: <5QQYd2N3zI@bion101.bionic.zer.de>
From: M.LIEBERMANN@BIONIC.zer.de (Martin Liebermann)
Subject: Re: Research information
Date: Tue, 07 Jun 1994 21:16:00 +0200

[text deleted -cak]

About BZ i found the following news in my archive:
---------------------snip------------------------------------------------------

Nachricht von    : bwhite@oucsace.cs.ohiou.edu (William E. White )
Betrifft         : Re: Your worst nightmare
Erstellungsdatum : 06.02.1994 14:19:29 W+0:00

In article ,
Joseph E. Gladstone  wrote:
>: Sounds like BZ to me. I guess it's closely related to nerve gas. The feature
>: film "Jacob's Ladder" portrayed BZ experiments in Vietnam during the war.
>: Jody

>No way - BZ lasts for quite a while depending on doseage, 8 - 72 hours.
>Cholinergics produce wierd effects, but not predictably nightmarish.

Actually, BZ (quinuclidinol benzilate, or QNB) is an anticholinergic,
acting specifically on muscarinic receptors.  It is extremely potent (and
is, in fact, used in research for its antimuscarinic properties).  It
also seems to have a greater LD50/ED50 ratio than other antimuscarinics
(such as atropine, scopolamine, etc).  But I wouldn't try it, it's still
not particularly safe.  Incidentally, it has been reported to tend to
induce nightmarish hallucinations/delusions (I could never find out why).
In any case, I can imagine that in a combat situation, one could easily
find onesself in a bad trip.


(Bad ASCII drawing to follow):


ASCII drawing of QNB (sorry, not too great.  The two rings on the top
and bottom are phenyl groups).


                          / \\
            N            ||  |
          / \ \      O    \ //
         |   | |     ||    |
         |   | |__O--C-----C--O--H
          \ / /            |
                          / \\
                         ||  |
                          \ //




--
|  Bill White   +1-614-594-3434     | bwhite@oucsace.cs.ohiou.edu             |
|  31 Curran Dr., Athens OH  45701  | bwhite@bigbird.cs.ohiou.edu (alternate) |
|  SCA: Erasmus Marwick, Dernehealde Pursuivant, Dernehealde, Middle Kingdom  |

---------------snap-----------------------------------------------------------


MK-801 I've never heard of.

Greetings

Martin Liebermann

M.Liebermann@bionic.zer.de  * PGP-key available *   fon/fax +49 +521 446729
## CrossPoint v3.02 R ##

=============================================================================

From: Lamont Granquist
Newsgroups: alt.drugs
Subject: Re: Research information
Date: 10 Jun 1994 04:56:42 GMT
Message-ID: <2t8rqa$1h8@news.u.washington.edu>

[quoted text deleted -cak]

--- forwarded from e-mail ---

From: Anonymous
To: Lamont Granquist
Subject: Re: Research information
Newsgroups: alt.drugs
Date: Tue, 7 Jun 94 18:52:05 EDT

BZ is the benzoicc acid ester of 3-Quinuclidinol.  I believe it was
explored as a chemical warfare incapicitating agent by the CIA.
I know Dr. James Moore who used to be a prof at the U of DE and 
made compounds for the CIA.  He tells some amazing tales.

Case in point:  He made BZ for the CIA and got some on his
hands.  He felt very disoriented.  "I felt like the whole world turned 
sideways on me." This effect lasted for days and so he asked the  big 
boys at the CIA how to get back.  They told him to take some THA 
(tetrahydroacridine) that is now used as an experimental Alzheimers 
treatment.   He claims it straightened him right out.

MK-801 is a sigma opiate receptor agonist (I think) not sure about that one.