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Dose
A standard oral dose of 5-MeO-MIPT is between 2 and 7 mg.
Price
5-MeO-MIPT is not available commercially and so there is no common price.
Law
5-MeO-MIPT is not specifically controlled in the United States, but could be considered an Analogue of 5-MeO-DIPT, a Schedule I drug, if it were intended for human use.
Chemistry
N-isopropyl-5-methoxy-N-methyl-tryptamine (5-MeO-MiPT) is a synthetic chemical tryptamine and thus is structurally related to other tryptamines (natural and synthetic), such as 5-MeO-DMT, N,N-DMT, psiloc(yb)in and serotonin.
History
The first publication of the synthesis and pharmacology of this compound was in 1985 in Journal of Medicinal Chemistry by Repke, Grotjahn & Shulgin [article].
Slang
The Substance: none
The Experience: tripping
Onset
Depending on how much and how recently the user has eaten, oral 5-MeO-MIPT generally takes 10-20 minutes to start to take effect. Smoked freebase usually comes on within seconds.
Duration
Due to the small number of reports and a wide variation in reported durations for this chemical, it is difficult to give reliable estimates of length of action. Some users have reported effects completely abating within 4-6 hours, while others have reported residual stimulation and inability to sleep for several additional hours.
The Experience
Oral 5-MeO-MIPT has some similarities with 5-MeO-DIPT. Users have reported aphrodisiac effects, minor changes in visual perception, mental stimulation, new perspectives, feelings of insight, emotional shifts, muscle tension, and mild tremor. The body load seems to be milder than with 5-MeO-DIPT. Sometimes there is a tendency of dreamy separation of mind and body as with 5-MeO-DMT. With the smoking route, more visuals and a "rush" are reported.
Addiction Potential
As with most psychedelics 5-MeO-MIPT seems to be neither physically addicting nor likely to cause psychological dependence. But as with all substances, some people will use it more frequently than they are comfortable with. There is a short period of tolerance after 5-MeO-MIPT use. Using it two days in a row is likely to lead to a diminished experience the second day, though spaced 5-7 or more days apart, this effect is nearly non-existent.
Contraindications
- 5-MeO-MIPT and MAOIs are a potentially dangerous combination. It is likely that MAOIs could increase the effects of 5MeO-MIPT unpredictably. Taking this chemical while on prescription MAOIs is strongly discouraged. MAOIs are most commonly found in the prescription anti-depressants Nardil (phenelzine), Parnate (tranylcypromine), Marplan (isocarboxazid), Eldepryl (l-deprenyl), and Aurorex or Manerix (moclobemide). Ayahuasca also contains MAOIs (harmine and harmaline). Check with your doctor if you are not sure whether your prescription medication is an MAOI.
- Do not operate heavy machinery. Do Not Drive.
- Individuals currently in the midst of emotional or psychological upheaval in their everyday lives should be careful about choosing to use psychedelics such as 5-MeO-MIPT as they can trigger even more difficulty.
- Individuals with a family history of schizophrenia or early onset mental illness should be extremely careful because psychedelics have been known to trigger latent psychological and mental problems.
- Combining multiple psychoactive tryptamines, such as taking 4-oxygenated tryptamines (e.g. psilocybin, 4-AcO-DIPT, 4-AcO-MIPT) with 5-oxygenated ones such as 5-MeO-MIPT or 5-MeO-DIPT, may lead to unexpected potentiation of the action of each substance. This means that low doses of each, in combination, may produce an unexpectedly strong action.
- Individuals with seizure or convulsive disorders or heart problems may be at higher risk for health problems when taking psychedelics. Diabetics should monitor their blood sugar closely, as there have been some reports of problems.
| Last Modified - Tue, Apr 24, 2007 | Created by Erowid |
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