5-MeO-DMT
Timeline
| Late 8th Century | Burial site in N. chile includes bag with snuffing paraphernalia and snuff remnants containing DMT, 5-MeO-DMT, & Bufotenine. Other sites include seeds of Anadenanthera spp. | |
| 1496 | Friar Ramon Pane documented the use of a psychoactive snuff called cohoba/yopo among the Taino who inhabited the island of Hispaniola (Haiti/Dominican Republic). It is now agreed that cohoba/yopo was almost certainly made from Anadenanthera peregrina which contains N,N-DMT, 5-MeO-DMT, and Bufotenin. 1 [Details] | |
| 16th - 19th Century | Cohoba snuff from the Yopo tree used by natives of Columbia and surrounding areas. | |
| 1560 | Indians along the Rio Guaviare in Colombia take Yopo along with tobacco. | |
| 1936 | 5-MeO-DMT is first synthesized [Disputed] 2 [Details] | |
| 1959 | 5-MeO-DMT is identified as one of the psychoactive ingredients of the A. peregrina seeds used to make cohoba snuff. This marked the first time that 5-MeO-DMT was discovered naturally occuring in a plant or animal. 3 | |
| 1968 | 5-MeO-DMT is found in the venom of the Bufo alvarius toad. | |
| 1970-1990 | There is some recreational use of 5-MeO-DMT, though the pure material is rare and difficult to come by. Smoking of bufo toad venom is probably the most common form of 5-MeO-DMT ingestion in the U.S. | |
| c. 1992 | 5-MeO-DMT becomes available commercially through mail-order. |
References
- Ott J. Shamanic Snuffs or Entheogenic Errhines. Entheobotanica, 2001.