5-MeO-DMT
Timeline
| Late 8th Century | Burial site in N. chile includes bag with snuffing paraphernalia and snuff remnants containing DMT, 5-MeO-DMT, & Bufotenine. Other sites include seeds of Anadenanthera spp. | |
| 1496 | Friar Ramon Pane documented the use of a psychoactive snuff called cohoba/yopo among the Taino who inhabited the island of Hispaniola (Haiti/Dominican Republic). It is now agreed that cohoba/yopo was almost certainly made from Anadenanthera peregrina which contains N,N-DMT, 5-MeO-DMT, and Bufotenin. 1 [Details] | |
| 16th - 19th Century | Cohoba snuff from the Yopo tree used by natives of Columbia and surrounding areas. | |
| 1560 | Indians along the Rio Guaviare in Colombia take Yopo along with tobacco. | |
| 1936 | 5-MeO-DMT is first synthesized [Disputed] 2 [Details] | |
| 1959 | 5-MeO-DMT is identified for the first time as a naturally occurring product, having been detected in the plant Dictyloma incanescens. 3 | |
| 1968 | 5-MeO-DMT is found in the venom of the Bufo alvarius toad. | |
| 1971-1987 | Starting around 1971 through the late 1980s, 5-MeO-DMT was discreetly available to members of the Church of the Tree of Life through the Inner Center. After 1987, the Inner Center began providing their sacraments to members of some religious groups as well. 4 [Details] | |
| 1970-1990 | There is some recreational use of 5-MeO-DMT, though the pure material is rare and difficult to come by. Smoking of bufo toad venom and limited availability on parsley through the Church of the Tree of Life are probably the most common forms of 5-MeO-DMT ingested in the U.S. during this period. | |
| c. 1992 | 5-MeO-DMT becomes available commercially through mail-order. |
References
- Ott J. Shamanic Snuffs or Entheogenic Errhines. Entheobotanica, 2001.
- Comments on DEA 331 PROPOSED RULE: Schedules of Controlled Substances: Placement of 5-Methoxy-N,N-Dimethyltryptamine Into Schedule I of the Controlled Substances Act and unpublished Erowid copies of the Inner Center documents

