Dose
A standard oral dose of 2C-I is between 10-25 mg. Recent reports suggest that 2C-I is just slightly more potent than 2C-B (slightly less material needed for the same level of effects).

Law
2C-I is an uncontrolled substance in the United States meaning that possession is not specifically illegal. It is possible that possession and sales could be prosecuted under the Federal Analog Act though we are unaware of any such existing cases. 2C-I is scheduled in Germany and Denmark, but not in the European Union (EU).

Chemistry
2,5-Dimethoxy-4-Iodophenethylamine (2C-I) is a synthetic chemical phenethylamine related structurally to 2C-B.

Production
The bulk of available 2C-I is primarily produced by experienced chemists in commercial labs.

History
2C-I first gained public awareness after the publication of PiHKAL by Alexander & Ann Shulgin.

Slang
The Substance: 2C-I
The Experience: tripping

Onset
Depending on how much and how recently the user has eaten, oral 2C-I takes between 45-75 minutes to take effect. On a full stomach, onset can be considerably slower.

Duration
The primary effects of 2C-I last approximately 5-8 hours when taken orally.

Contraindications

• Do not take 2C-I if you are currently taking an MAOI. MAOIs are most commonly found in the prescription anti-depressants Nardil (phenelzine), Parnate (tranylcypromine), Marplan (isocarboxazid), Eldepryl (l-deprenyl), and Aurorex or Manerix (moclobemide). Ayahuasca also contains MAOIs (harmine and harmaline). 2C-I and MAOIs are a potentially dangerous combination. Check with your doctor if you are not sure whether your prescription medication is an MAOI.
  
  
• Do not operate heavy machinery. Do Not Drive.
  
  
• Individuals currently in the midst of emotional or psychological upheaval in their everyday lives should be careful about choosing to use psychedelics such as 2C-I as they can trigger even more difficulty.
  
  
• Individuals with a family history of schizophrenia or early onset mental illness should be extremely careful because psychedelics have been known to trigger latent psychological and mental problems.