================================================================= This file is a part of the 1999 Hyperreal Drug Archives Snapshot. This snapshot is hosted by Erowid and will not be updated after October 1999. The information in these files may be out of date. See Erowid's Psychoactive Vaults for more current info. ================================================================= From: lamont@hyperreal.com (Lamont Granquist) Newsgroups: alt.drugs Subject: chemistry: secrets of methamphetmine manufacuring... Date: 10 Jun 1994 08:27:36 GMT Message-ID: <2t985o$4kr@news.u.washington.edu> Ephedrine and pseudoephedrine are structurally mirror images of each other. This is possible because they have a chiral center, the isopropyl carbon to which the nitrogen atom is attached. If the reduction is done in such a manner that the chiral nature of the substance is not jumbled (i.e. racemization), then ephedrine and pseudoephedrine give rise to "l" and "d" methamphetamine, respectively. The "l" form is several times more potent than the "d" form. Meth produced from phenylacetone is a racemic mixture, meaning that it is a 50-50 mix of the "l" and "d" forms of meth. Obviously, a batch of pure "l" form is most desireable, a racemic mixture is OK, and pure "d" form is bad news. "Uncle Fester" needs to do more research. l-ephedrine does give rise to the more potent *d* form of methamphetamine. both OTC ephedrine and pseudoephedrine should be useful for the synthesis (provided that it is d-pseudoephedrine which is sold OTC -- which is the natural isomer). My guess is that Fester extrapolated from using "l-ephedrine" to getting "l-methamphetamine" which is quite wrong... I'm not terribly impressed with this guy... -- Lamont Granquist (lamont@hyperreal.com) "And then the alien anthropologists - Admitted they were still perplexed - But on eliminating every other reason - For our sad demise - They logged the only explanation left - This species has amused itself to death" -- Roger Waters