Illustrated Synthesis of MDA from Safrole
Ever wonder how NASA gets so high? This is how they make rocket fuel.
p-Benzoquinone Wacker oxidation and ketone purification
Drip just started.
Done with dripping
Acid/H2O flood and buchner filter out precipitate
Seperation in seperatory funnel
IR nightvision of seperation of 1st NaOH wash
Second NaOH wash seperation
Proper vacuum distilation rig setup with fractionating column pic 1
Proper vacuum distilation rig setup with fractionating column pic 2
Proper vacuum distilation rig setup with fractionating column pic 3
Ketone distillation temperature
Ketone in recieving flask
NaBH3CN Reductive amination and seperation of freebase
NaBH3CN reduction and apperatus. Reduction just started.
Reaction through completion pic 1
Reaction through completion pic 2
Reaction through completion pic 3
Reaction through completion pic 4
Removing the MeOH
Acid wash with DCM extraction of unreacted ketone
Aq layer made basic dropping freebase out of solution
Basic Aq layer washed with DCM, removing additional freebase
Freebase in DCM
Gassing and product recovery
HCl gassing of freebase in DCM just began!
DCM thick with precipitated HCl salt
HCl salt buchner filtered from DCM
Filter cake after acetone wash
There it is!