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From: mmanzo@mail.sas.upenn.edu (Marco Manzo)
Newsgroups: alt.drugs
Subject: FAQ list-Opioid Analgesics
Date: 29 May 1994 19:16:02 GMT
Message-ID: <2sapli$nca@netnews.upenn.edu>


As suggested in the "Hydromorphone, Oxymorphone" thread, here is a
sort of FAQ-list/summary of the opioid pain killers available in the
United States.

CATEGORY I.  STRONG AGONISTS-- SEVERE PAIN
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
generic name	trade name	recommended	duration	Controlled
				dosage		of action	substance
								category

HYDROMORPHONE	DILAUDID	2-4 mg. every	4-5 hours	Schedule II
				4-6  hours.			narcotic
dosages avail: 1,2,3,4,10 mg.tabs    
Parenteral (injection) 1,2,3,4 mg./mL ampules

LEVORPHANOL	LEVO-DROMORAN	2-3 mg. every	4-5 hours	Schedule II
				6-8 hours			narcotic
dosages: 2 mg. tabs; injection: 2 mg./mL

MEPERIDINE	DEMEROL		50-150 mg. 	2-4 hours	Schedule II
				every 3-4 hours			narcotic
dosages: 50,100 mg. tabs; 
injection: 25,50,75,100 mg. vials

METHADONE	DOLOPHINE	40 mg. every	4-6 hours	Schedule II
dosages: 5,10,40 mg. tabs;	24 hours;			Narcotic
injection: 10 mg./mL		2.5-10 mg.injection   the oral form is used
				every 3-4 hours       only in detoxification
						      programs

MORPHINE SULFATE 		varies: 10-30 mg. 4-5 hours	Schedule II
dosages: 10,15,30 mg. tabs;	every 4 hours;			Narcotic
injection: 2,4,5,8,10,15 mg/mL	30 mg. controlled 
				release tablets
			        every 8-12 hours
				
OXYMORPHONE	NUMORPHON	5 mg. supppository  3-4 hours	Schedule II
dosages: 5 mg. suppos.		every 4-6 hours;		Narcotic
1, 1.5 mg/mL injection		1-1.5 mg. injection
				every 4-6 hours.

STRONG AGONISTS FOR INJECTION ONLY:

FENTANYL	SUBLIMAZE	0.05-0.1 mg.	   1-1.5 hours	Schedule II
dosages: 0.05 mg./mL for	repeat in 2 hours		Narcotic
injection			if necessary

SUFENTANIL	SUFENTA		1-30 micrograms/kg.		Schedule II
dosages: 50 micrograms		injected as needed for		Narcotic
per mL in 1,2,5 mL ampules	anesthesia

ALFENTANIL	ALFENTA		0.5-3 micrograms/kg./minute	Schedule II
dosages: 500 micrograms/mL	IV infusion in balanced anesthesia
ampules for injection


CATEGORY II -- MILD TO MODERATE AGONISTS  - MODERATE TO SEVERE PAIN
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
GENERIC NAME	TRADE NAME	RECOMMENDED	DURATION OF	CONTROLLED
				DOSAGE		ACTION		SUBSTANCE
								CATEGORY
						
CODEINE  SULFATE OR PHOSPHATE	15-60 mg. every	 3-4 hours	Schedule II
dosages: 15,30,60 mg. tablets;	4-6 hours		(when combined with
30,60 mg./mL for injection			     acetominophen or asprin
							it is a
							Schedule III Narcotic)

OXYCODONE	PERCODAN (with asprin)
		PERCOCET (with tylenol)
dosages: 5 mg. oxycodone per tablet
				5 mg. every 	3-4 hours	Schedule II
				6 hours				Narcotic

HYDROCODONE	VICODIN,LORTAB	5-7 mg. every	3-4 hours	Schedule III
BITARTRATE	LORCET, HYDROCET 4-6 hours			Narcotic
dosages: either 2.5, 5, or 7 mg.
hydrocodone with either asprin or tylenol


CATEGORY III -- WEAK AGONISTS -- MILD TO MODERATE PAIN
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
GENERIC NAME	TRADE NAME	RECOMM. DOSAGE	  DURATION OF	CONTROLLED
						  ACTION	SUBSTANCE
								CATEGORY

PROPOXYPHENE	DARVON		50-100 mg. every  4-5 hours	Schedule IV
PROPOXYPHENE			4 hours				Narcotic
NAPSYLATE	DARVOCET N-50
		DARVOCET N-100


CATEGORY IV -- MIXED AGONISTS/ANTAGONISTS -- MODERATE TO SEVERE PAIN
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
GENERIC NAME	TRADE NAME	RECOMM. DOSAGAE	 DURATION OF	CONTROLLED
						 ACTION		SUBSTANCE
								CATEGORY

PENTAZOCINE	TALWIN-NX	50-100 mg.	  3 hours	Schedule IV
dosages: 50 mg. tablets;	every 3-4 hours;		Narcotic
30 mg./mL in 1 and 2 mL		30 mg. injection (Pentazocine is mixed
ampules for injection		every 3-4 hours  with Naxolone [an opiate
					    antagonist] to prevent crushing
				     of tabs. for intravenous injection)
OTHER MIXED AGONIST-ANTAGONISTS:

BUPRENORPHINE	BUPRENEX					Schedule V
dosage: 0.3 mg./mL ampules for injection.

BUTORPHANOL	STADOL
dosage: 1 and 2 mg./mL vials and syringes for injection
Not a controlled substance because of the strong antagonist efficacy

NALBUPHINE	NUBAIN
dosage: 10 and 20 mg./mL vials and syringes for injection
Not a controlled substance because of the strong antagonist efficacy